Anastrozole

Anastrozole

  • Anastrozole

Product Description

Anastrozole

Identification

Name

Anastrozole

Synonyms

Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile

Molecular Structure

Molecular Formula

C17H19N5

Molecular Weight

293.37

CAS Registry Number

120511-73-1

Properties

Melting point

81-82 ºC

Appearance: white crystal powder

Medicinal categories: non-steroidal aromatase inhibitors

Indication: Anastrozole is used for Postmenopausal women with advanced breast cancer that tamoxifen and other anti-estrogen therapy cannot control. For the estrogen receptor-negative patients, can think about the anastrozole if the tamoxifen showed positive clinical response

Pharmacology: Anastrozole as a potent, selective nonsteroidal aromatase inhibitors, it can inhibit the postmenopausal patients with adrenal suppression generated androstenedione intoestrone, significantly reduce plasma estrogen levels. And inhibiting of breast tumor growth. Anastrozole significantly affect on adrenal corticosteroids or aldosterone.

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