Anastrozole
Product Description
Anastrozole |
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Identification |
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Name |
Anastrozole |
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Synonyms |
Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile |
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Molecular Structure |
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Molecular Formula |
C17H19N5 |
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Molecular Weight |
293.37 |
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CAS Registry Number |
120511-73-1 |
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Properties |
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Melting point |
81-82 ºC |
Appearance: white crystal powder
Medicinal categories: non-steroidal aromatase inhibitors
Indication: Anastrozole is used for Postmenopausal women with advanced breast cancer that tamoxifen and other anti-estrogen therapy cannot control. For the estrogen receptor-negative patients, can think about the anastrozole if the tamoxifen showed positive clinical response
Pharmacology: Anastrozole as a potent, selective nonsteroidal aromatase inhibitors, it can inhibit the postmenopausal patients with adrenal suppression generated androstenedione intoestrone, significantly reduce plasma estrogen levels. And inhibiting of breast tumor growth. Anastrozole significantly affect on adrenal corticosteroids or aldosterone.
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